There is a dilemma when people have to stop taking the new obesity drugs
Zepbound: A Drug that Can Help You Feel Like You’re Frinking: Natalie Muth, MD, a Pediatrician, and a Supporter
There are many emotional changes to prepare for, too, says Dr. Natalie Muth, a pediatrician and spokesman for the American Academy of Pediatrics.
The particulars of biology, genetics, or hormonal makeup will affect a person’s response to being on the drug. She says that biology favors regain for most people. “We as humans – it’s evolutionary to want to store this fat and want to keep it on.”
There is a new GLP-1 agonistdrug called Zepbound that can help you feel free from hunger. He doesn’t consume as much and moves as much without the gnawing need to eat.
Instead, he bought the drugs at the compound pharmacy in Florida. He did so with his doctor’s cautious blessing and despite the various unknowns — like what’s in the drug, exactly, or how he might react to it.
Source: The new obesity drugs work, but it’s a dilemma when people have to stop taking them
What is the worst nightmare of losing weight in adults with Obesity? Discussion of Dr. Rekha Kumar on the use of social media to convince people to stop taking their prescribed medications
He says that after two weeks on the substitute, it is a mixed bag. He feels dyspeptic on it, but also hungrier. It’s difficult to push the plate aside as I want a little bit more.
He says that even the hassles of uncertainty like short supply, fluctuating cost, and long-term effects are worth it. “To me, if I have GI problems for the rest of my life, but I don’t have a heart attack or don’t have all the other things associated with obesity, it’s fine.”
“So there are going to be scenarios, especially in young people, [where] we will have to come off the medicine, whether they like it or not,” Kumar says.
Kumar believes that transitioning on and off the drugs will be a reality for many patients when they are still on the drugs, because of situations like surgery or pregnant women. (To date, research on pregnant women and GLP1 medications suggest it is not linked to more birth defects than insulin, but the full impact of fetal exposure is not yet known. Drug companies warn that contraceptives may become less effective if women use GLP1 medicines, because they report pregnancies after using them.
And so far, clinical data seem to back up Meyers’ suspicions. One early study showed patients regained two-thirdsof the weight lost within the first year of stopping. According to the new analysis, more than one in five people can keep 80% of their weight loss after stopping. lifestyle choices like food and activity are necessary in order for long term weightloss plans, but they can’t be the only option for patients with Obesity.
These are also blockbuster medicines and have become a societal phenomenon. And all the chatter about the use of them on social media and in popular culture can confuse patients, says Dr. Rekha Kumar, an endocrinologist and former medical director of the American Board of Obesity Medicine. She says social media is often used by people to convince people that they should use an obese medication short term in order to begin a diet.
In other words: Chronic disease requires chronic treatment, no different than kidney disease, or high cholesterol. There are various drivers of weight gain and loss, with new obesity treatments acting on them.
He felt his hunger won out in the end before he got the injections. This whole thing is the biggest component, he says. He says he doesn’t need to grab a candy bar if he walks past it in the grocery store.
More and more people are taking GLP-1 agonists because they help with weight loss but aren’t good for permanent hair loss. But because of cost, for example, negative side effects, or supply shortages, many people are having to transition off of them — while trying not to regain the weight.
Jonathan Meyers: Growing Up, Fatting, Undeservingly Wanting to Get Glue and Stay Well: A Journey Through the Dark Side of Life
The drug is hard to find due to being in short supply. Meyers even had family in Maine ship medicine in cold containers to him in Kensington, Maryland. Now, he can’t find Zepbound anywhere, and says friends, family, and people he follows on social media are all in the same boat. Many have turned to online compound pharmacies in order to get an approximation of the drug.
Over the past few decades, Jonathan Meyers endured several cycles of gaining, shedding, then regaining weight after attempting Keto, high protein, low fat, and calorie-restrictive diets. Meyers, a digital strategist at the environmental nonprofit, says he always regains his weight after success, up and down.
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U.S. firefighters face shortage after Rafah airstrike: condemnation by the United Nations and global condemnation against Israel
Israel is receiving international condemnation following an airstrike on Rafah on Sunday that caused a fire at a tented area for displaced people. At least 45 Palestinians were killed and dozens more were injured in the attack. The military said it wasn’t expecting to harm civilians when it targeted the Hamas installation. Netanyahu called the mistake a “tragic mistake”. The U.N. relief chief said that if it were to be called a mistake it wouldn’t have any meaning for those killed, grieving or trying to save lives.
As wildfires burn in Canada and Mexico, U.S. fire officials are concerned about the upcoming wildfire season. Upwards of a quarter of the government’s wildland firefighting jobs are vacant. Pay is low and the risks are high for rookies. Forests are overgrown, and rising heat and drought add to the dangers. People who take the firefighting jobs cannot afford to live in the places where they work. 🎧 The labor shortage isn’t new, especially since the pandemic, NPR’s Kirk Siegler says. The federal government will likely continue using private contractors or borrowing crews from Mexico and Canada — strategies Siegler says are “not ideal.”
Source: U.S. faces firefighter shortage; global condemnation toward Israel mounts
How a Virginia IT Firm Solved the Arthur Grand Jobs Controversy: A Civil Penalty from the Justice Department and the Department of Labor
A Virginia-based IT staffing firm settled with the Justice Department and the Department of Labor after a job posting came under fire for including race and citizenship requirements. Only Born US Citizens were sought in the Arthur Grand Technologies listing. White is from within 60 miles of Dallas, TX. [Don’t share with candidates].” Arthur Grand will pay a civil penalty of $7,500, along with a total of $31,000, to 31 people who complained about the posting. Arthur Grands CEO said in a statement to NPR that his company denies any guilt or wrongdoing, and that a rogue employee made the job posting.
On New Year’s Eve, the Okalolies of the island of Staten Island come to life. Old Year’s Night is a time when young men dressed in masks and costumes wreak havoc on their town. There is a very tightly guarded secret about where the Okalolies are going and who they are. In the new year, people on the island ring in with dancing and barbecues known as braais.
